Advances in understanding cancer-associated neurogenesis and …
This review discusses the effects of nerve cells, immune cells, and cancer cells have on each other that regulate neurogenesis, cancer progression, and dissemination.
Tumor-induced neurogenesis and immune evasion as targets of …
Jun 18, 2020 · Tumor-derived neurogenesis occurs when cancer stem cells differentiate to neuron-like cells, particularly to autonomic neurons that release neurotransmitters to enrich the tumor...
Role of the nervous system in cancers: a review
Apr 12, 2021 · Cancer cells track along or around a nerve after infiltrating into perineural space in the process of nerve injury, which in turn promotes neural regeneration.
The neuroscience of cancer - Nature
Jun 14, 2023 · This emerging field of ‘cancer neuroscience’ encompasses local and systemic interactions between cancer cells and the fundamental components of the nervous system—neurons, astrocytes,...
Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk
Mar 15, 2021 · Recent research has shown that cancer cells express neurotrophic markers such as nerve growth factor, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor and release axon-guidance molecules such as ephrin B1 to promote axonogenesis.
Tumor-induced neurogenesis and immune evasion as targets of ... - PubMed
Jun 18, 2020 · The neurogenic switch, activated by tumor-derived neurotrophins and extracellular vesicles, attracts adjacent peripheral fibers (autonomic/sensorial) and neural progenitor cells. Strikingly, tumor-associated nerve fibers can guide cancer cell dissemination.
Roadmap for the Emerging Field of Cancer Neuroscience - Cell …
Apr 16, 2020 · Mounting evidence indicates that the nervous system plays a central role in cancer pathogenesis. In turn, cancers and cancer therapies can alter nervous system form and function. This Commentary seeks to describe the burgeoning field of “cancer neuroscience” and encourage multidisciplinary collaboration for the study of cancer-nervous ...
Advances in understanding cancer-associated neurogenesis and …
Abstract. Nerves and immunologic mediators play pivotal roles in body homeostasis by interacting with each other through diverse mechanisms. The spread of nerves in the tumor microenvironment increases tumor cell proliferation and disease progression, and this correlates with poor patient outcomes.
Cancer hallmarks intersect with neuroscience in the tumor ...
Mar 13, 2023 · The mechanisms underlying the multistep process of tumorigenesis can be distilled into a logical framework involving the acquisition of functional capabilities, the so-called hallmarks of cancer, which are collectively envisaged to be necessary for malignancy.
Integrating priorities at the intersection of cancer and …
2 days ago · Cancer neuroscience is an interdisciplinary field that focuses on the intricate relationship between the nervous system and cancer. Growing evidence supports the involvement of the central and peripheral nervous systems in the onset, development, and spread of cancer. 1, 2, 3 This unique area of investigation has seen remarkable growth over the past two decades, with scholarly articles ...